Melatonin. Mitochondria. Mitophagy. Autophagy. Oh my! Back pain connects them all interestingly.
Melatonin – the sleep regulating hormone – manages sleep which
is essential to the body’s capability to recover
from the day and get ready for the next. Mitophagy stimulates healthy
turnover of mitochondria (the energy producers in cells). Mitophagy prevents
the build-up of abnormal mitochondria in cells that may lead
to cell degeneration. In the case of back pain,
this would avoid such deterioration in the cells of the disc which may lead to disc
degeneration. Autophagy is a normal practice
that manages cell destruction and creation in the
body. When there is cellular stress, autophagy is augmented.
(1) Capitol Spine & Rehabilitation shares findings that melatonin
and light therapy may intervene in this process and help with
Baton Rouge back pain relief.
MITOCHONDRIA AND DISC DEGENERATION
Capitol Spine & Rehabilitation understands how disc degeneration includes cellular oxidative stress, mitochondria issues and cell death (aka
apoptosis). This is where researchers suggest
melatonin may perform a beneficial role in the slowing
of disc degeneration. Melatonin gets rid of oxygen free radicals,
normalizes mitochondria function and balance, hastens mitrophagy and slows apoptosis (cell death).
Melatonin may help treat disc degeneration. (2)
MELATONIN AND LIGHT FOR DISC DEGENERATION AND Baton Rouge BACK PAIN
In a biological study of melatonin’s effect on intervertebral
disc degeneration, melatonin sustained nucleus
pulposus cells influenced by oxidative stress. Such stress leads
to damage of these cells. Melatonin is an vital
neuroendocrine hormone with sound antioxidant effect that functions
on biological clock regulation. (3) Chronic non-specific low back pain
sufferers who added melatonin to their treatment
plan found it to positively increase the
effect of standard treatments on pain, sleep and depression. The reduced
pain intensity when moving and resting indicated that melatonin
potentially offers an analgesic
effect. (4) Melatonin may be another way to treat intervertebral disc degeneration.
LIGHT THERAPY AND BACK PAIN RELIEF
Since melatonin is activated
by light and its lack, light treatment helps patients handle chronic low back pain, its pain intensity, behavior, and
threshold. It also helps
with post-traumatic stress disorders symptomatology and quality of sleep. All
these were bettered with morning bright light treatment of US
veterans with chronic low back pain. (5) Such treatment could surely
help Baton Rouge back pain sufferers, too! These researchers believe
that this light treatment regulates the circadian timing of sleep which
is mediated by melatonin. (5)
CONTACT Capitol Spine & Rehabilitation
Listen to the PODCAST
with Dr. Chris DeVeau on the Back Doctors Podcast with Dr. Michael
Johnson. A patient struggling with neck pain and arm pain found
difficulty with sleep and relief with Cox® Technic.
Schedule a Baton Rouge chiropractic appointment for
your Baton Rouge back pain. Patients in Baton Rouge with disc degeneration may find
extra relief with melatonin and light therapy alongside chiropractic treatment. Mitochondria, mitophagy, autophagy,
melatonin and back pain are interestingly linked, aren’t they?